AT-090

Modify Date: 2024-04-03 17:13:20

AT-090 Structure
AT-090 structure
Common Name AT-090
CAS Number 2099681-59-9 Molecular Weight 354.494
Density N/A Boiling Point N/A
Molecular Formula C22H30N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AT-090


AT-090 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM; displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.

 Names

Name AT-090

 AT-090 Biological Activity

Description AT-090 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM; displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.
References References 1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13. 2. Asth L, et al. Neuropharmacology. 2016 Jun;105:434-442. View Related Products by Target Opioid Receptor

 Chemical & Physical Properties

Molecular Formula C22H30N2O2
Molecular Weight 354.494
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