2099681-59-9
2099681-59-9 structure
- Name: AT-090
- Chemical Name: AT-090
- CAS Number: 2099681-59-9
- Molecular Formula: C22H30N2O2
- Molecular Weight: 354.494
- Create Date: 2020-01-11 18:09:50
- Modify Date: 2025-08-26 01:58:24
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AT-090 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM; displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.
| Name | AT-090 |
|---|
| Description | AT-090 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM; displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists. |
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| References | References 1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13. 2. Asth L, et al. Neuropharmacology. 2016 Jun;105:434-442. View Related Products by Target Opioid Receptor |
| Molecular Formula | C22H30N2O2 |
|---|---|
| Molecular Weight | 354.494 |