2099680-72-3
2099680-72-3 structure
- Name: AT-127
- Chemical Name: AT-127
- CAS Number: 2099680-72-3
- Molecular Formula: C22H31N3O2
- Molecular Weight: 369.509
- Create Date: 2020-01-20 14:48:56
- Modify Date: 2025-08-24 23:03:58
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AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM; displays >60-fold selectivity over mu and kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.
| Name | AT-127 |
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| Description | AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM; displays >60-fold selectivity over mu and kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists. |
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| References | References 1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13. View Related Products by Target Opioid Receptor |
| Molecular Formula | C22H31N3O2 |
|---|---|
| Molecular Weight | 369.509 |