Berberine

Modify Date: 2024-01-02 09:19:40

Berberine Structure
Berberine structure
Common Name Berberine
CAS Number 2086-83-1 Molecular Weight 336.361
Density N/A Boiling Point N/A
Molecular Formula C20H18NO4+ Melting Point 204-206ºC (dec.)
MSDS N/A Flash Point N/A

 Use of Berberine


Berberine is a natural alkaline, reduces apoptosis, with potent anti-oxidative and anti-inflammatory effect[1].

 Names

Name berberine
Synonym More Synonyms

 Berberine Biological Activity

Description Berberine is a natural alkaline, reduces apoptosis, with potent anti-oxidative and anti-inflammatory effect[1].
Related Catalog
References

[1]. Ma X, et al. Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis. Exp Ther Med. 2019 Sep;18(3):2122-2130.

 Chemical & Physical Properties

Melting Point 204-206ºC (dec.)
Molecular Formula C20H18NO4+
Molecular Weight 336.361
Exact Mass 336.123047
PSA 40.80000
LogP -0.99

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DR9870000
CHEMICAL NAME :
Berbinium, 7,8,13,13a-tetrahydro-9,10-dimethoxy-2,3-(methylenedi oxy)-
CAS REGISTRY NUMBER :
2086-83-1
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C20-H18-N-O4
MOLECULAR WEIGHT :
336.39
WISWESSER LINE NOTATION :
T F5 D6 C666 GO IO ON HH&&T&&J RO1 SO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
329 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
10 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981

 Safety Information

Hazard Codes Xi
Safety Phrases S24/25
RIDADR UN 1544
WGK Germany 2
RTECS DR9866400
Packaging Group III
Hazard Class 6.1(b)
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Berberine
EINECS 211-195-9
5,6-Dihydro-9,10-dimethoxybenzo[g]1,3-benzodioxolo[5,6-a]quinolizinium
9,10-Dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium
9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium
Berberin
1,3-Benzodioxolo[5,6-a]benzo[g]quinolizinium, 5,6-dihydro-9,10-dimethoxy-
5,6-dihydro-9,10-dimethoxy-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
MFCD00011939
5,6-dihydro-9,10-dimethoxy-1,3-benzodioxolo[5,6-a]benzo[g]quinolizinium
7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium
Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Berberine
  • Price: ¥Inquiry/20mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng





Get all suppliers and price by the below link:

Berberine suppliers

Berberine price