Allocryptopine

Modify Date: 2024-01-02 22:11:10

Allocryptopine Structure
Allocryptopine structure
Common Name Allocryptopine
CAS Number 485-91-6 Molecular Weight 369.411
Density 1.2±0.1 g/cm3 Boiling Point 552.7±50.0 °C at 760 mmHg
Molecular Formula C21H23NO5 Melting Point N/A
MSDS N/A Flash Point 288.1±30.1 °C

 Use of Allocryptopine


Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].

 Names

Name allocryptopine
Synonym More Synonyms

 Allocryptopine Biological Activity

Description Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].
Related Catalog
References

[1]. Xu B, et al. Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol. Evid Based Complement Alternat Med. 2015;2015:634172.

[2]. Lin K, et al. Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacol Sin. 2013 Jun;34(6):847-58.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 552.7±50.0 °C at 760 mmHg
Molecular Formula C21H23NO5
Molecular Weight 369.411
Flash Point 288.1±30.1 °C
Exact Mass 369.157623
PSA 57.23000
LogP 3.64
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.574
Storage condition 2-8C

 Synthetic Route

 Synonyms

allo-Cryptopine
Allocryptopine
β-Homochelidonine
Benzo[c][1,3]benzodioxolo[5,6-g]azecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-
[1,3]Benzodioxolo[5,6-e][2]benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-
5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one
5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one
Thalictrimine
Fagarine I
a-allo-Cryptopine
Benzo(e)(1,3)dioxolo(4,5-k)(3)benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-
3,4-Dimethoxy-6-methyl-5,7,8,15-tetrahydrobenzo[c][1,3]benzodioxolo[5,6-g]azecin-14(6H)-one
α-Fagarine
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