TB 21007

Modify Date: 2024-09-26 18:08:10

TB 21007 Structure
TB 21007 structure
Common Name TB 21007
CAS Number 207306-50-1 Molecular Weight 339.49600
Density N/A Boiling Point N/A
Molecular Formula C15H17NO2S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TB 21007


TB-21007 is an inverse agonist of α5β3γ2 subunit-containing GABAA receptor with a Ki of 1.6 nM. TB-21007 enhanced spatial memory in rats[1].

 Names

Name 3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
Synonym More Synonyms

 TB 21007 Biological Activity

Description TB-21007 is an inverse agonist of α5β3γ2 subunit-containing GABAA receptor with a Ki of 1.6 nM. TB-21007 enhanced spatial memory in rats[1].
Related Catalog
References

[1]. Chambers MS, et al. Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition. J Med Chem. 2003 May 22;46(11):2227-40.

 Chemical & Physical Properties

Molecular Formula C15H17NO2S3
Molecular Weight 339.49600
Exact Mass 339.04200
PSA 131.97000
LogP 4.11110

 Synonyms

Methyl 2,5-dihydroxycinnamate
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