TB 21007

Names

[ CAS No. ]:
207306-50-1

[ Name ]:
TB 21007

[Synonym ]:
Methyl 2,5-dihydroxycinnamate

Biological Activity

[Description]:

TB-21007 is an inverse agonist of α5β3γ2 subunit-containing GABAA receptor with a Ki of 1.6 nM. TB-21007 enhanced spatial memory in rats[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. Chambers MS, et al. Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition. J Med Chem. 2003 May 22;46(11):2227-40.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₇NO₂S₃

[ Molecular Weight ]:
339.49600

[ Exact Mass ]:
339.04200

[ PSA ]:
131.97000

[ LogP ]:
4.11110

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.