4-PPBP maleate
Modify Date: 2024-01-04 18:47:30
4-PPBP maleate structure
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Common Name | 4-PPBP maleate | ||
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| CAS Number | 201216-39-9 | Molecular Weight | 409.518 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H31NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-PPBP maleate4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection[1][2][3]. |
| Name | 4-Phenyl-1-(4-phenylbutyl)piperidine (2Z)-2-butenedioate (1:1) |
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| Synonym | More Synonyms |
| Description | 4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection[1][2][3]. |
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| Related Catalog | |
| In Vitro | 4-PPBP maleate elicits ERK1/2 phosphorylation in primary neurons[3]. |
| In Vivo | 4-PPBP maleate (1 μmol/kg; i.v.) decreases brain injury after transient focal ischemia in rats[2]. Animal Model: Male rats weighing 300 to 385 g (Transient focal ischemia model)[2] Dosage: 1 μmol/kg Administration: Per hour by continuous intravenous infusion starting 1 hour after the initiation of ischemia and continuing through 22 hours of reperfusion. Result: Decreased brain injury after transient focal ischemia in rats. |
| References |
| Molecular Formula | C25H31NO4 |
|---|---|
| Molecular Weight | 409.518 |
| Exact Mass | 409.225311 |
| 4-Phenyl-1-(4-phenylbutyl)piperidine (2Z)-but-2-enedioate (1:1) |
| 4-Phenyl-1-(4-phenylbutyl)piperidine (2Z)-2-butenedioate (1:1) |
| Piperidine, 4-phenyl-1-(4-phenylbutyl)-, (2Z)-2-butenedioate (1:1) |