ZCZ011

Modify Date: 2024-01-18 12:28:26

ZCZ011 Structure
ZCZ011 structure
Common Name ZCZ011
CAS Number 1998197-39-9 Molecular Weight 362.44
Density 1.3±0.1 g/cm3 Boiling Point 602.8±55.0 °C at 760 mmHg
Molecular Formula C21H18N2O2S Melting Point N/A
MSDS N/A Flash Point 318.4±31.5 °C

 Use of ZCZ011


ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain[1].

 Names

Name ZCZ-011
Synonym More Synonyms

 ZCZ011 Biological Activity

Description ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain[1].
Related Catalog
Target

CB1[1]

References

[1]. Ignatowska-Jankowska BM, et al. A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects. Neuropsychopharmacology. 2015;40(13):2948-2959.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 602.8±55.0 °C at 760 mmHg
Molecular Formula C21H18N2O2S
Molecular Weight 362.44
Flash Point 318.4±31.5 °C
Exact Mass 362.108887
LogP 6.37
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.677

 Safety Information

Hazard Codes Xi

 Synonyms

ZCZ011
1H-Indole, 6-methyl-3-[2-nitro-1-(2-thienyl)ethyl]-2-phenyl-
ZCZ-011
6-Methyl-3-[2-nitro-1-(2-thienyl)ethyl]-2-phenyl-1H-indole
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