PF-04745637
Modify Date: 2025-08-25 16:41:45
PF-04745637 structure
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Common Name | PF-04745637 | ||
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| CAS Number | 1917294-46-2 | Molecular Weight | 509.0033896 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H32ClF3N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-04745637PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1[1]. |
| Name | 1-(4-chlorophenyl)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)cyclopentanecarboxamide |
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| Synonym | More Synonyms |
| Description | PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1[1]. |
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| Related Catalog | |
| Target |
TRPA1:17 nM (IC50) |
| In Vivo | Topically applied PF-04745637 (Compound 8; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin[1]. |
| References |
| Molecular Formula | C27H32ClF3N2O2 |
|---|---|
| Molecular Weight | 509.0033896 |
| PF-04745637 |