Rimeporide

Modify Date: 2024-01-02 12:02:33

Rimeporide Structure
Rimeporide structure
Common Name Rimeporide
CAS Number 187870-78-6 Molecular Weight 333.38400
Density N/A Boiling Point N/A
Molecular Formula C11H15N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Rimeporide


Rimeporide is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

 Names

Name N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide
Synonym More Synonyms

 Rimeporide Biological Activity

Description Rimeporide is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).
Related Catalog
Target

NHE1[1]

In Vitro Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].
References

[1]. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.

 Chemical & Physical Properties

Molecular Formula C11H15N3O5S2
Molecular Weight 333.38400
Exact Mass 333.04500
PSA 167.50000
LogP 2.96170
Storage condition 2-8℃

 Synonyms

Rimeporide
UNII-QH6B4V5743
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Rimeporide
  • Price: $750.0/100mg $1200.0/250mg $2500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: $190/1mg

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