GSK-3β inhibitor 1

Modify Date: 2024-01-08 11:53:34

GSK-3β inhibitor 1 Structure
GSK-3β inhibitor 1 structure
Common Name GSK-3β inhibitor 1
CAS Number 187325-53-7 Molecular Weight 222.24
Density N/A Boiling Point N/A
Molecular Formula C14H10N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK-3β inhibitor 1


GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

 Names

Name GSK-3β inhibitor 1

 GSK-3β inhibitor 1 Biological Activity

Description GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
Related Catalog
Target

GSK-3β:4.9 nM (IC50)

References

[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.

 Chemical & Physical Properties

Molecular Formula C14H10N2O
Molecular Weight 222.24
Storage condition -20°C