GPR40 agonist 1

Modify Date: 2025-08-25 17:32:26

GPR40 agonist 1 Structure
GPR40 agonist 1 structure
Common Name GPR40 agonist 1
CAS Number 1853982-41-8 Molecular Weight 479.54
Density N/A Boiling Point N/A
Molecular Formula C27H30FN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GPR40 agonist 1


GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.

 Names

Name GPR40 agonist 1

 GPR40 agonist 1 Biological Activity

Description GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.
Related Catalog
Target

EC50: 2 nM (hGPR40), 17 nM (rGPR40)[1]

References

[1]. Meegalla SK, et al. Discovery of a novel potent GPR40 full agonist. Bioorg Med Chem Lett. 2018 Feb 15;28(4):720-726.

 Chemical & Physical Properties

Molecular Formula C27H30FN3O4
Molecular Weight 479.54
InChIKey FNXMDDKBLZLDDD-NRFANRHFSA-N
SMILES COc1cc(-c2ncc(COc3cccc(C(CC(=O)O)C4CC4)c3)nc2CC(C)C)c(F)cn1
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