Loganin

Modify Date: 2024-01-02 20:09:00

Loganin structure	Common Name	Loganin
	CAS Number	18524-94-2	Molecular Weight	390.382
	Density	1.5±0.1 g/cm3	Boiling Point	608.8±55.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₆O₁₀	Melting Point	222°C
	MSDS	Chinese USA	Flash Point	217.9±25.0 °C

Use of Loganin

Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation.

Name	loganin
Synonym	More Synonyms

Description	Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Terpenoids and Glycosides
References	[1]. Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50. [2]. Tsai WH, et al. Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourol Urodyn. 2015 Aug 19.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Others

Natural Products >> Terpenoids and Glycosides

References

[1]. Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50.

[2]. Tsai WH, et al. Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourol Urodyn. 2015 Aug 19.

Density	1.5±0.1 g/cm3
Boiling Point	608.8±55.0 °C at 760 mmHg
Melting Point	222°C
Molecular Formula	C₁₇H₂₆O₁₀
Molecular Weight	390.382
Flash Point	217.9±25.0 °C
Exact Mass	390.152588
PSA	155.14000
LogP	-2.73
Vapour Pressure	0.0±4.0 mmHg at 25°C
Index of Refraction	1.600

Loganin MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R22
Safety Phrases	S22-S45
RIDADR	1544
WGK Germany	3

Precursor 7
CAS#:20586-11-2 methyl (1S,4aS,... CAS#:139501-37-4 Ligustrinoside CAS#:71462-04-9 1-O,6-O-Diacety... CAS#:186581-53-3 diazomethane
CAS#:82509-41-9 8-Epiloganic acid CAS#:80054-38-2 (6E)-8-hydroxy-... CAS#:26660-57-1 Deoxyloganin
DownStream 4
CAS#:132237-63-9 (4R)-Hexahydro-... CAS#:132339-37-8 (4S)-Hexahydro-... CAS#:19351-63-4 Secologanin CAS#:99891-77-7 Isoboonein acetate

Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica.

Biol. Pharm. Bull. 34(8) , 1330-3, (2011)

Allergy-preventive activity of flower buds of Lonicera japonica THUNB. was found in the 35% EtOH extract (LJ) using an in vivo assay, The assay system uses monitoring of a decrease in blood flow (BF) ...

[Optimization of microwave-assisted extraction with RSM and HPLC determination for three iridoid glycosides in Cornus officinalis].

Zhong Yao Cai 34(7) , 1118-22, (2011)

To establish a method of microwave-assisted extraction and high performance liquid chromatographic (HPLC) for simultaneous determination of three iridoid glycosides including loganin, sweroside and co...

Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica.

Biosci. Biotechnol. Biochem. 74(10) , 2022-8, (2010)

The parenteral route has many merits over the oral route, including greater predictability, reproducibility of absorption, and rapid drug action, but injectable phytomedicines are uncommon due to prot...

7-HYDROXY-6-DESOXYVERBENALIN

(1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-6-hydroxy-7-méthyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate de méthyle

Loganoside

Cuchiloside

Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, (1S,4aS,6S,7R,7aS)-

Methyl (1S,4aS,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate

LOGANINE

Loganin

MFCD00075645

(1S,4aS,6S,7R,7aS)-6-Hydroxy-7-méthyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate de méthyle

loganic acid methyl ester

Methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate

1-(b-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester

Methyl-(1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylat

Loganin, loganoside

Meliatin

EINECS 242-398-0

BioBioPha
China
Product Name: Loganin
Price: ￥Inquiry/50mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Loganin
Price: ￥398.0/20mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Loganin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Loganin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Price: ￥452.4/10mg

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Loganin

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