CPI-1189

Modify Date: 2024-01-09 14:56:46

CPI-1189 Structure
CPI-1189 structure
Common Name CPI-1189
CAS Number 183619-38-7 Molecular Weight 234.294
Density 1.1±0.1 g/cm3 Boiling Point 458.3±28.0 °C at 760 mmHg
Molecular Formula C13H18N2O2 Melting Point N/A
MSDS N/A Flash Point 183.9±24.2 °C

 Use of CPI-1189


CPI-1189 is a TNF-α release inhibitor with antioxidant and neuroprotective properties. CPI-1189 is used for researches of HIV-associated neurotoxicity and thus is a candidate for neuroprotective therapy in humans suffered from HIV-associated CNS disease[1][2].

 Names

Name 4-Acetamido-N-tert-butylbenzamide
Synonym More Synonyms

 CPI-1189 Biological Activity

Description CPI-1189 is a TNF-α release inhibitor with antioxidant and neuroprotective properties. CPI-1189 is used for researches of HIV-associated neurotoxicity and thus is a candidate for neuroprotective therapy in humans suffered from HIV-associated CNS disease[1][2].
Related Catalog
References

[1]. Müller T. CPI-1189. Centaur. Curr Opin Investig Drugs. 2002 Dec;3(12):1763-7.

[2]. Clifford DB, et al. A randomized clinical trial of CPI-1189 for HIV-associated cognitive-motor impairment. Neurology. 2002 Nov 26;59(10):1568-73.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 458.3±28.0 °C at 760 mmHg
Molecular Formula C13H18N2O2
Molecular Weight 234.294
Flash Point 183.9±24.2 °C
Exact Mass 234.136826
LogP 1.38
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.553
Storage condition -20℃

 Synonyms

4-Acetamido-N-(2-methyl-2-propanyl)benzamide
Benzamide, 4-(acetylamino)-N-(1,1-dimethylethyl)-
MFCD00774476
4-Acetamido-N-tert-butylbenzamide
CPI-1189
REN-1189
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