PF-06456384 trihydrochloride
Modify Date: 2025-09-24 13:47:51
PF-06456384 trihydrochloride structure
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Common Name | PF-06456384 trihydrochloride | ||
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| CAS Number | 1834610-75-1 | Molecular Weight | 719.799 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 789.8±70.0 °C at 760 mmHg | |
| Molecular Formula | C35H32F3N7O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 431.4±35.7 °C | |
Use of PF-06456384 trihydrochloridePF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 trihydrochloride can be used for parkinson's disease (PD) research[1]. |
| Name | 3-Cyano-4-({3-[2-({[2-(4-piperidinyl)ethyl]amino}methyl)-4-pyridinyl]-3'-(trifluoromethyl)-4-biphenylyl}oxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide |
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| Synonym | More Synonyms |
| Description | PF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 trihydrochloride can be used for parkinson's disease (PD) research[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 789.8±70.0 °C at 760 mmHg |
| Molecular Formula | C35H32F3N7O3S2 |
| Molecular Weight | 719.799 |
| Flash Point | 431.4±35.7 °C |
| Exact Mass | 719.195984 |
| LogP | 6.95 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.666 |
| 3-Cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-benzenesulfonamide trihydrochloride |
| Benzenesulfonamide, 3-cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-, hydrochloride (1:3) |
| Benzenesulfonamide, 3-cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl- |
| 3-Cyano-4-({3-[2-({[2-(4-piperidinyl)ethyl]amino}methyl)-4-pyridinyl]-3'-(trifluoromethyl)-4-biphenylyl}oxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide |