PF-4878691

Modify Date: 2025-08-21 19:46:39

Use of PF-4878691

PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.

Name	N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide
Synonym	More Synonyms

Description	PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	TLR7[1]
References	[1]. Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691). Clin Pharmacol Ther. 2011 Jun;89(6):821-9.

Molecular Formula	C₁₇H₂₃N₅O₂S
Molecular Weight	361.46200
Exact Mass	361.15700
PSA	112.01000
LogP	3.46030
InChIKey	YZOQZEXYFLXNKA-UHFFFAOYSA-N
SMILES	CCc1nc2c(N)nc3ccccc3c2n1CCCCNS(C)(=O)=O
Storage condition	2-8℃

N/A

CAS#:960254-09-5

PF-4878691

CAS#:532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ; Location in patent: Page/Page column 36 ;

N/A

CAS#:960254-05-1

PF-4878691

CAS#:532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ;

N-4-(4-aminobut...

CAS#:723282-40-4

PF-4878691

CAS#:532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ;

Precursor 1
CAS#:723282-40-4 N-4-(4-aminobut...
DownStream 0

UNII-6PJC3KPK6S

N-(4-(4-Amino-2-ethyl-imidazo(4,5-c)quinolin-1-yl)butyl)methanesulfonamide

N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methansulfonamide

852A

Methanesulfonamide, N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-

PF-4878691

Get all suppliers and price by the below link:

Price: $1315/1mg

Reference only. check more PF-4878691 price