532959-63-0

532959-63-0 structure

Name: PF-4878691
Chemical Name: N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide
CAS Number: 532959-63-0
Molecular Formula: C₁₇H₂₃N₅O₂S
Molecular Weight: 361.46200
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2016-09-14 07:20:43
Modify Date: 2025-08-21 19:46:39
PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.

Name	N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide
Synonyms	UNII-6PJC3KPK6S N-(4-(4-Amino-2-ethyl-imidazo(4,5-c)quinolin-1-yl)butyl)methanesulfonamide N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methansulfonamide 852A Methanesulfonamide, N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]- PF-4878691

Description	PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	TLR7[1]
References	[1]. Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691). Clin Pharmacol Ther. 2011 Jun;89(6):821-9.

960254-09-5

532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ; Location in patent: Page/Page column 36 ;

960254-05-1

532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ;

723282-40-4

532959-63-0

Literature: Coley Pharmaceutical Group, Inc. Patent: US2011/269965 A1, 2011 ;

Precursor 1
723282-40-4
DownStream 0