PF-06456384

Modify Date: 2025-08-23 18:44:07

PF-06456384 Structure
PF-06456384 structure
 Common Name PF-06456384
CAS Number 1834610-73-9 Molecular Weight 719.80
Density N/A Boiling Point N/A
Molecular Formula C35H32F3N7O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF-06456384


PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1].

 Names

Name PF-06456384

 PF-06456384 Biological Activity

Description PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1].
Related Catalog
References

[1]. Jaclyn L Henderson, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.

 Chemical & Physical Properties

Molecular Formula C35H32F3N7O3S2
Molecular Weight 719.80
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Chemsrc provides PF-06456384(CAS#:1834610-73-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PF-06456384 are included as well.>> amp version: PF-06456384

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