MLT-748
Modify Date: 2024-07-17 20:05:58
MLT-748 structure
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Common Name | MLT-748 | ||
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| CAS Number | 1832578-30-9 | Molecular Weight | 492.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H19Cl2N9O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MLT-748MLT-748 is an allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM. MLT-748 also reversibly binds to human mutant MALT1(329-728)-W580S (Kd, 13 nM) with affinity similar to that of the wild type MALT1(329-728) (Kd, 42 nM)[1]. |
| Name | MLT-748 |
|---|
| Description | MLT-748 is an allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM. MLT-748 also reversibly binds to human mutant MALT1(329-728)-W580S (Kd, 13 nM) with affinity similar to that of the wild type MALT1(329-728) (Kd, 42 nM)[1]. |
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| Related Catalog | |
| Target |
IC50: 5 nM (MALT1)[1] Kd: 13 nM (MALT1(329-728)-W580S), 42 nM (MALT1(329-728))[1] |
| References |
| Molecular Formula | C19H19Cl2N9O3 |
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| Molecular Weight | 492.32 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
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