(R)-MLT-985

Modify Date: 2024-01-09 15:13:46

(R)-MLT-985 structure	Common Name	(R)-MLT-985
	CAS Number	1832577-07-7	Molecular Weight	448.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅Cl₂N₉O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-MLT-985

(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells[1].

Name	(R)-MLT-985

Description	(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> NF-κB >> MALT1
References	[1]. Jean Quancard, et al. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood. J Med Chem. 2020 Dec 10;63(23):14594-14608.

Molecular Formula	C₁₇H₁₅Cl₂N₉O₂
Molecular Weight	448.27

DC Chemicals Limited
China
Product Name: (R)-MLT-985
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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