GIP (3-42), human

Modify Date: 2024-01-10 08:14:06

GIP (3-42), human Structure
GIP (3-42), human structure
Common Name GIP (3-42), human
CAS Number 1802086-25-4 Molecular Weight 4749.9
Density N/A Boiling Point N/A
Molecular Formula C216H325F3N58O65S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GIP (3-42), human


GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo[1].

 Names

Name Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt
Synonym More Synonyms

 GIP (3-42), human Biological Activity

Description GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo[1].
Related Catalog
In Vitro The incretin hormone GIP is rapidly degraded in the circulation by dipeptidyl peptidase IV (DPP IV) forming the N-terminally truncated peptide GIP(3-42)[1].
References

[1]. V A Gault, et al. Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo. J Endocrinol. 2002 Nov;175(2):525-33.

 Chemical & Physical Properties

Molecular Formula C216H325F3N58O65S
Molecular Weight 4749.9
Storage condition -20°C

 Synonyms

MFCD18782440