Defensin HNP-3 (human) trifluoroacetate salt

Modify Date: 2024-01-12 21:22:45

Defensin HNP-3 (human) trifluoroacetate salt Structure
Defensin HNP-3 (human) trifluoroacetate salt structure
Common Name Defensin HNP-3 (human) trifluoroacetate salt
CAS Number 136661-76-2 Molecular Weight 3486.04
Density N/A Boiling Point N/A
Molecular Formula C151H222N44O40S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Defensin HNP-3 (human) trifluoroacetate salt


Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].

 Names

Name α-DEFENSIN-3 (HUMAN)
Synonym More Synonyms

  Biological Activity

Description Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].
Related Catalog
References

[1]. Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9.  

[2]. Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435.

 Chemical & Physical Properties

Molecular Formula C151H222N44O40S6
Molecular Weight 3486.04
Exact Mass 3439.51000
PSA 1474.93000
LogP 6.05340

 Synonyms

Defensin HNP-3 (human)