Defensin HNP-3 (human) trifluoroacetate salt

Names

[ Name ]:
Defensin HNP-3 (human) trifluoroacetate salt

[Synonym ]:
Defensin HNP-3 (human)

Biological Activity

[Description]:

Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9.

[2]. Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅₁H₂₂₂N₄₄O₄₀S₆

[ Molecular Weight ]:
3486.04

[ Exact Mass ]:
3439.51000

[ PSA ]:
1474.93000

[ LogP ]:
6.05340

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.