MMAF sodium
Modify Date: 2025-09-21 09:15:37
MMAF sodium structure
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Common Name | MMAF sodium | ||
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| CAS Number | 1799706-65-2 | Molecular Weight | 753.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C39H64N5NaO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MMAF sodiumMMAF sodium (Monomethylauristatin F sodium) is an antitubulin agent that inhibit cell division; attenuates its cytotoxic activity compared to MMAE. MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. |
| Name | MMAF sodium |
|---|
| Description | MMAF sodium (Monomethylauristatin F sodium) is an antitubulin agent that inhibit cell division; attenuates its cytotoxic activity compared to MMAE. MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. |
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| Related Catalog | |
| In Vitro | MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC50s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay. |
| References |
| Molecular Formula | C39H64N5NaO8 |
|---|---|
| Molecular Weight | 753.94 |
| InChIKey | LGMDBXMBHWLORJ-KMYLZLQDSA-M |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1ccccc1)C(=O)[O-])OC)N(C)C(=O)C(NC(=O)C(NC)C(C)C)C(C)C.[Na+] |