β-catenin-IN-37
Modify Date: 2025-08-25 11:18:43
β-catenin-IN-37 structure
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Common Name | β-catenin-IN-37 | ||
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| CAS Number | 1783856-40-5 | Molecular Weight | 307.277 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H9N9O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of β-catenin-IN-37β-catenin-IN-37 is a novel potent, and selective small-molecule inhibitor for the β-catenin/Tcf4 protein-protein interaction with Ki of 17 uM; suppresses canonical Wnt signaling, downregulates the expression of Wnt target genes; inhibits the growth of Wnt-activated cancer cells with the IC50 values of 26 uM and 31 uM for SW480 and HCT116 cells, respectively. |
| Name | β-catenin-IN-37 |
|---|
| Description | β-catenin-IN-37 is a novel potent, and selective small-molecule inhibitor for the β-catenin/Tcf4 protein-protein interaction with Ki of 17 uM; suppresses canonical Wnt signaling, downregulates the expression of Wnt target genes; inhibits the growth of Wnt-activated cancer cells with the IC50 values of 26 uM and 31 uM for SW480 and HCT116 cells, respectively. |
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| References | References 1. Catrow JL, et al. J Med Chem. 2015 Jun 11;58(11):4678-92. View Related Products by Target Beta-catenin |
| Molecular Formula | C13H9N9O |
|---|---|
| Molecular Weight | 307.277 |