8-HYDROXYWARFARIN
8-HYDROXYWARFARIN structure
|
Common Name | 8-HYDROXYWARFARIN | ||
|---|---|---|---|---|
| CAS Number | 17834-04-7 | Molecular Weight | 324.32700 | |
| Density | 1.384g/cm3 | Boiling Point | 519.6ºC at 760mmHg | |
| Molecular Formula | C19H16O5 | Melting Point | 185-187ºC | |
| MSDS | Chinese USA | Flash Point | 189.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Density | 1.384g/cm3 |
|---|---|
| Boiling Point | 519.6ºC at 760mmHg |
| Melting Point | 185-187ºC |
| Molecular Formula | C19H16O5 |
| Molecular Weight | 324.32700 |
| Flash Point | 189.3ºC |
| Exact Mass | 324.10000 |
| PSA | 87.74000 |
| LogP | 3.31520 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.659 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2932209090 |
|
~55%
8-HYDROXYWARFARIN CAS#:17834-04-7 |
| Literature: Obaseki, Andrew O.; Steffen, James E.; Porter, William R. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 529 - 533 |
|
~%
8-HYDROXYWARFARIN CAS#:17834-04-7 |
| Literature: Drug Metabolism and Disposition, , vol. 41, # 7 p. 1295 - 1299 |
|
~%
8-HYDROXYWARFARIN CAS#:17834-04-7 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 22, p. 529 - 533 |
|
~%
8-HYDROXYWARFARIN CAS#:17834-04-7 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 22, p. 529 - 533 |
|
~%
8-HYDROXYWARFARIN CAS#:17834-04-7 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 22, p. 529 - 533 |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers.
J. Chromatogr. A. 1363 , 200-6, (2014) Several offline and online 2D HPLC methods were investigated for the reversed phase resolution of a complex mixture of closely related warfarin and hydroxywarfarin isomers. By combining reversed phase... |
|
|
Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.
Chem. Res. Toxicol. 23(5) , 939-45, (2010) Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta... |
|
|
Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins.
Drug Metab. Lett. 6(3) , 157-64, (2012) Coumadin (R/S-warfarin) is a highly efficacious and widely used anticoagulant; however, its highly variable metabolism remains an important contributor to uncertainties in therapeutic responses. Pharm... |
| 8-Hydroxywarfarin |