7-hydroxy Warfarin
7-hydroxy Warfarin structure
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Common Name | 7-hydroxy Warfarin | ||
|---|---|---|---|---|
| CAS Number | 17834-03-6 | Molecular Weight | 324.33 | |
| Density | 1.384g/cm3 | Boiling Point | 540.2ºC at 760mmHg | |
| Molecular Formula | C19H16O5 | Melting Point | 220ºC | |
| MSDS | Chinese USA | Flash Point | 197.7ºC | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
Use of 7-hydroxy Warfarin7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity[1]. |
| Name | 7-Hydroxy Warfarin |
|---|---|
| Synonym | More Synonyms |
| Description | 7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.384g/cm3 |
|---|---|
| Boiling Point | 540.2ºC at 760mmHg |
| Melting Point | 220ºC |
| Molecular Formula | C19H16O5 |
| Molecular Weight | 324.33 |
| Flash Point | 197.7ºC |
| Exact Mass | 324.10000 |
| PSA | 87.74000 |
| LogP | 3.31520 |
| Vapour Pressure | 1.68E-12mmHg at 25°C |
| Index of Refraction | 1.658 |
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2932209090 |
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7-hydroxy Warfarin CAS#:17834-03-6 |
| Literature: Xenobiotica, , vol. 28, # 2 p. 103 - 115 |
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7-hydroxy Warfarin CAS#:17834-03-6 |
| Literature: Drug Metabolism and Disposition, , vol. 41, # 7 p. 1295 - 1299 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.
Drug Metab. Dispos. 43 , 1408-16, (2015) The common marmoset (Callithrix jacchus), a small New World monkey, has the potential for use in human drug development due to its evolutionary closeness to humans. Four novel cDNAs, encoding cytochro... |
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Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers.
J. Chromatogr. A. 1363 , 200-6, (2014) Several offline and online 2D HPLC methods were investigated for the reversed phase resolution of a complex mixture of closely related warfarin and hydroxywarfarin isomers. By combining reversed phase... |
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Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.
Chem. Res. Toxicol. 23(5) , 939-45, (2010) Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta... |
| 7-Hydroxywarfarin |
| 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one |