Orphanin FQ(1-11) structure
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Common Name | Orphanin FQ(1-11) | ||
|---|---|---|---|---|
| CAS Number | 178249-41-7 | Molecular Weight | 1098.212 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C49H75N15O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Orphanin FQ(1-11)Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice[1][2]. |
| Name | L-Phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-N5-(diaminomethylene)-L-ornithyl-L-lysyl-L-seryl-L-alanine |
|---|---|
| Synonym | More Synonyms |
| Description | Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C49H75N15O14 |
| Molecular Weight | 1098.212 |
| Exact Mass | 1097.561768 |
| LogP | -2.33 |
| Index of Refraction | 1.648 |
| InChIKey | BBTOUBACUUPBRQ-KCKZSKPYSA-N |
| SMILES | CC(NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccccc1)C(C)O)C(=O)O |
| L-Alanine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-N5-(diaminomethylene)-L-ornithyl-L-lysyl-L-seryl- |
| L-Phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-N5-(diaminomethylene)-L-ornithyl-L-lysyl-L-seryl-L-alanine |