Monensin

Modify Date: 2025-10-23 13:39:30

Monensin structure	Common Name	Monensin
	CAS Number	17090-79-8	Molecular Weight	670.871
	Density	1.2±0.1 g/cm3	Boiling Point	766.3±60.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₆₁NaO₁₁	Melting Point	103-105°C
	MSDS	N/A	Flash Point	229.2±26.4 °C

Use of Monensin

Monensin is a lipid-soluble naturally occurring bioactive ionophore produced by Streptomyces spp. Monensin can bind protons and monovalent cations. Monensin exhibits a broad spectrum activity against opportunistic pathogens of humans in both drug sensitive and resistant strains. Monensin also induces apoptosis in multiple cancer cell lines[1][2].

Name	monensin A
Synonym	More Synonyms

Description	Monensin is a lipid-soluble naturally occurring bioactive ionophore produced by Streptomyces spp. Monensin can bind protons and monovalent cations. Monensin exhibits a broad spectrum activity against opportunistic pathogens of humans in both drug sensitive and resistant strains. Monensin also induces apoptosis in multiple cancer cell lines[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Rajendran V, et, al. Chemotherapeutic Potential of Monensin as an Anti-microbial Agent. Curr Top Med Chem. 2018; 18(22): 1976-1986. [2]. Vanneste M, et, al. High content screening identifies monensin as an EMT-selective cytotoxic compound. Sci Rep. 2019 Feb 4; 9(1):1200.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Rajendran V, et, al. Chemotherapeutic Potential of Monensin as an Anti-microbial Agent. Curr Top Med Chem. 2018; 18(22): 1976-1986.

[2]. Vanneste M, et, al. High content screening identifies monensin as an EMT-selective cytotoxic compound. Sci Rep. 2019 Feb 4; 9(1):1200.

Density	1.2±0.1 g/cm3
Boiling Point	766.3±60.0 °C at 760 mmHg
Melting Point	103-105°C
Molecular Formula	C₃₆H₆₁NaO₁₁
Molecular Weight	670.871
Flash Point	229.2±26.4 °C
Exact Mass	670.429199
PSA	156.20000
LogP	3.72
Vapour Pressure	0.0±5.9 mmHg at 25°C
Index of Refraction	1.546
InChIKey	GAOZTHIDHYLHMS-SJOFMCCUSA-N
SMILES	CCC1(C2OC(C3OC(O)(CO)C(C)CC3C)CC2C)CCC(C2(C)CCC3(CC(O)C(C)C(C(C)C(OC)C(C)C(=O)O)O3)O2)O1
Storage condition	2-8°C

Hazard Codes	T: Toxic;
Risk Phrases	R25
Safety Phrases	S36/37/39-S45
RIDADR	UN 3462 6.1/PG 2
WGK Germany	3
RTECS	JH2830000
Packaging Group	II
Hazard Class	6.1(a)

Precursor 1
CAS#:22373-78-0 Monensin sodium salt
DownStream 2
CAS#:1297518-94-5 CAS#:2387-23-7 1,3-Dicyclohexylurea

1,6-Dioxaspiro[4.5]decane-7-butanoic acid, 2-[(2S,2'R,3'S,5R,5'R)-2-ethyloctahydro-3'-methyl-5'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9- ;hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, (αS,βR,γS,2S,5R,7S,8R,9S)-

monensicacid

Monensin

Elancoban

Monelan

Romensin

MONENSIN SODIUM

1,6-dioxaspiro[4.5]decane-7-butanoic acid, 2-[(2S,2'R,3'S,5R,5'R)-2-ethyloctahydro-3'-methyl-5'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-b-methoxy-a,g,2,8-tetramethyl-, (aS,bR,gS,2S,5R,7S,8R,9S)-

MONENSIN(PURE)

MFCD00077826

EINECS 244-941-7

a3823a

1,6-dioxaspiro[4.5]decane-7-butanoic acid, 2-[(2S,2'R,3'S,5R,5'R)-2-ethyloctahydro-3'-methyl-5'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-, (αS,βR,γS,2S,5R,7S,8R,9S)-

(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid

MONENSIN NA

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Purity: 98.0%
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Monensin

Use of Monensin

Names

Monensin Biological Activity

Chemical & Physical Properties

Safety Information

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.