4-Maleimidobenzoic acid

Modify Date: 2025-08-23 18:27:10

4-Maleimidobenzoic acid structure	Common Name	4-Maleimidobenzoic acid
	CAS Number	17057-04-4	Molecular Weight	217.178
	Density	1.5±0.1 g/cm3	Boiling Point	447.1±28.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	224.2±24.0 °C

Use of 4-Maleimidobenzoic acid

4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers[1].

Name	4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
Synonym	More Synonyms

Description	4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers[1].
Related Catalog	Research Areas >> Others
References	[1]. Lau A, et, al. Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents. Bioorg Med Chem. 1995 Oct;3(10):1299-304.

Density	1.5±0.1 g/cm3
Boiling Point	447.1±28.0 °C at 760 mmHg
Molecular Formula	C₁₁H₇NO₄
Molecular Weight	217.178
Flash Point	224.2±24.0 °C
Exact Mass	217.037506
PSA	74.68000
LogP	0.77
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.669

Hazard Codes	Xi: Irritant;
Risk Phrases	36
Safety Phrases	26
HS Code	2925190090

4-[[(E)-3-carbo...

CAS#:5432-04-2

~91%

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Koechel; Tarloff; Rankin Journal of Medicinal Chemistry, 1983 , vol. 26, # 1 p. 85 - 90

Maleic anhydride

CAS#:108-31-6

4-Aminobenzoic acid

CAS#:150-13-0

~84%

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Hulubei, Camelia Revue Roumaine de Chimie, 2008 , vol. 53, # 9 p. 743 - 752

4-Aminobenzoic acid

CAS#:150-13-0

Maleic acid

CAS#:110-16-7

~93%

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Alagic, Amer; Koprianiuk, Agnieszka; Kluger, Ronald Journal of the American Chemical Society, 2005 , vol. 127, # 22 p. 8036 - 8043

4-(3-carboxypro...

CAS#:36847-93-5

~70%

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Anand, Preet; Singh, Baldev Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 521 - 530

4-Aminobenzoic acid

CAS#:150-13-0

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 1 p. 521 - 530

Maleic anhydride

CAS#:108-31-6

4-Nitrobenzoic acid

CAS#:62-23-7

~99%

4-Maleimidobenz...

CAS#:17057-04-4

Literature: Hoveyda, Hamid R.; Hall, Dennis G. Organic Letters, 2001 , vol. 3, # 22 p. 3491 - 3494

Precursor 6
CAS#:5432-04-2 4-[[(E)-3-carbo... CAS#:108-31-6 Maleic anhydride CAS#:150-13-0 4-Aminobenzoic acid CAS#:110-16-7 Maleic acid
CAS#:36847-93-5 4-(3-carboxypro... CAS#:62-23-7 4-Nitrobenzoic acid
DownStream 5
CAS#:29305-46-2 4-(2,5-dioxopyr... CAS#:123457-83-0 4-(MALEINIMIDO)... CAS#:64191-06-6 4-N-MALEIMIDOBE... CAS#:57-13-6 Urea
CAS#:40349-49-3 methyl 4-(2,5-d...

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-(N-Maleimido)benzoic acid

MFCD00458571

4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-benzoic acid

Benzoic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-

EINECS 241-117-9

4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid

4-Maleimidobenzoic acid

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4-Maleimidobenzoic acid

Use of 4-Maleimidobenzoic acid

Names

4-Maleimidobenzoic acid Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.