Z-Pro-Pro-aldehyde-dimethyl acetal
Modify Date: 2025-08-26 11:58:34
Z-Pro-Pro-aldehyde-dimethyl acetal structure
|
Common Name | Z-Pro-Pro-aldehyde-dimethyl acetal | ||
|---|---|---|---|---|
| CAS Number | 170116-63-9 | Molecular Weight | 376.447 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 522.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H28N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 269.8±30.1 °C | |
Use of Z-Pro-Pro-aldehyde-dimethyl acetalZ-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease[1][2]. |
| Name | Benzyl (2S)-2-{[(2S)-2-(dimethoxymethyl)-1-pyrrolidinyl]carbonyl}-1-pyrrolidinecarboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease[1][2]. |
|---|---|
| Related Catalog | |
| Target |
PREP:12 nM (IC50) |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.5±50.0 °C at 760 mmHg |
| Molecular Formula | C20H28N2O5 |
| Molecular Weight | 376.447 |
| Flash Point | 269.8±30.1 °C |
| Exact Mass | 376.199829 |
| LogP | 1.33 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.554 |
| Benzyl (2S)-2-{[(2S)-2-(dimethoxymethyl)-1-pyrrolidinyl]carbonyl}-1-pyrrolidinecarboxylate |
| 1-Pyrrolidinecarboxylic acid, 2-[[(2S)-2-(dimethoxymethyl)-1-pyrrolidinyl]carbonyl]-, phenylmethyl ester, (2S)- |