7-Desmethyl-3-hydroxyagomelatine

Modify Date: 2025-08-25 11:30:49

7-Desmethyl-3-hydroxyagomelatine structure	Common Name	7-Desmethyl-3-hydroxyagomelatine
	CAS Number	166527-00-0	Molecular Weight	245.2738
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₅NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 7-Desmethyl-3-hydroxyagomelatine

7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine[1]. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[1][2].

Name	7-DesMethyl-3-hydroxyagoMelatine

Description	7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine[1]. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Melatonin Receptor Signaling Pathways >> GPCR/G Protein >> Melatonin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	MT1 MT2 5-HT2C Receptor
References	[1]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6. [2]. Kennedy SH, et al. Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatr Dis Treat. 2007 Aug;3(4):423-8.

Molecular Formula	C₁₄H₁₅NO₃
Molecular Weight	245.2738
InChIKey	FMUHSDLSKQLNNB-UHFFFAOYSA-N
SMILES	CC(=O)NCCc1cc(O)cc2ccc(O)cc12

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 7-Desmethyl-3-hydroxyagomelatine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: 7-Desmethyl-3-hydroxyagomelatine
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: 7-Desmethyl-3-hydroxyagomelatine
Price: $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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