FD-IN-1
Modify Date: 2025-08-27 16:21:17
FD-IN-1 structure
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Common Name | FD-IN-1 | ||
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| CAS Number | 1646682-14-5 | Molecular Weight | 377.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H23NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FD-IN-1FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1]. |
| Name | FD-IN-1 |
|---|
| Description | FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C23H23NO4 |
|---|---|
| Molecular Weight | 377.43 |
| InChIKey | XHLXBWRISOPXQB-OAQYLSRUSA-N |
| SMILES | NC(CO)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1 |