CDP 840 hydrochloride

Modify Date: 2024-01-30 08:35:59

CDP 840 hydrochloride Structure
CDP 840 hydrochloride structure
Common Name CDP 840 hydrochloride
CAS Number 162542-90-7 Molecular Weight 373.49
Density 1.122g/cm3 Boiling Point 489.9ºC at 760 mmHg
Molecular Formula C25H27NO2 Melting Point N/A
MSDS N/A Flash Point 174.3ºC

 Use of CDP 840 hydrochloride


CDP-840 (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP-840 inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys[1].

 Names

Name 4-[2-(3-cyclopentyloxy-4-methoxyphenyl)-2-phenylethyl]pyridine

 CDP 840 hydrochloride Biological Activity

Description CDP-840 (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP-840 inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys[1].
Related Catalog
Target

PDE4

References

[1]. Jones TR, et al. Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma. Can J Physiol Pharmacol. 1998 Feb;76(2):210-7.

 Chemical & Physical Properties

Density 1.122g/cm3
Boiling Point 489.9ºC at 760 mmHg
Molecular Formula C25H27NO2
Molecular Weight 373.49
Flash Point 174.3ºC
Exact Mass 373.20400
PSA 31.35000
LogP 5.78620
Vapour Pressure 2.88E-09mmHg at 25°C
Index of Refraction 1.591

 Synthetic Route

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