ZD 2079

Modify Date: 2024-01-08 19:40:17

ZD 2079 Structure
ZD 2079 structure
Common Name ZD 2079
CAS Number 178600-17-4 Molecular Weight 351.82500
Density N/A Boiling Point 524.3ºC at 760mmHg
Molecular Formula C18H22ClNO4 Melting Point N/A
MSDS N/A Flash Point 270.9ºC

 Use of ZD 2079


Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect[1].

 Names

Name 2-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethoxy]phenyl]acetic acid,hydrochloride
Synonym More Synonyms

 ZD 2079 Biological Activity

Description Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Talibegron hydrochloride has potent vasorelaxant effect[1].
Related Catalog
In Vitro Talibegron hydrochloride (ZD2079 hydrochloride; 0.01-1000 μM) produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries and causes full relaxation with 1 mM[1].
References

[1]. Hanna Kozłowska, et al. Atypical beta-adrenoceptors, different from beta 3-adrenoceptors and probably from the low-affinity state of beta 1-adrenoceptors, relax the rat isolated mesenteric artery. Br J Pharmacol. 2003 Sep;140(1):3-12.

 Chemical & Physical Properties

Boiling Point 524.3ºC at 760mmHg
Molecular Formula C18H22ClNO4
Molecular Weight 351.82500
Flash Point 270.9ºC
Exact Mass 351.12400
PSA 78.79000
LogP 3.20860
Vapour Pressure 8.06E-12mmHg at 25°C

 Synonyms

Talibegron hydrochloride
Talibegron HCl
CDP 840 hydrochloride
ZD 2079
ICID2079
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