162542-90-7

162542-90-7 structure

Name: CDP 840 hydrochloride
Chemical Name: 4-[2-(3-cyclopentyloxy-4-methoxyphenyl)-2-phenylethyl]pyridine
CAS Number: 162542-90-7
Molecular Formula: C₂₅H₂₇NO₂
Molecular Weight: 373.49
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2016-09-13 19:29:38
Modify Date: 2025-08-25 21:28:23
CDP-840 (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP-840 inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys[1].

Name	4-[2-(3-cyclopentyloxy-4-methoxyphenyl)-2-phenylethyl]pyridine

Description	CDP-840 (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP-840 inhibits antigen-induced early and late phase bronchoconstriction in conscious squirrel monkeys[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
Target	PDE4
References	[1]. Jones TR, et al. Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma. Can J Physiol Pharmacol. 1998 Feb;76(2):210-7.