PF-06250112
Modify Date: 2025-09-21 13:07:33
PF-06250112 structure
|
Common Name | PF-06250112 | ||
|---|---|---|---|---|
| CAS Number | 1609465-89-5 | Molecular Weight | 438.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H20F2N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06250112PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively[1]. |
| Name | PF-06250112 |
|---|
| Description | PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.5 nM (BTK), 0.9 nM (BMX), 1.2 nM (TEC)[1] |
| References |
| Molecular Formula | C22H20F2N6O2 |
|---|---|
| Molecular Weight | 438.43 |
| InChIKey | SQFDBQCBXUWICP-HNNXBMFYSA-N |
| SMILES | N#CN1CCCC(n2nc(-c3ccc(Oc4ccc(F)cc4F)cc3)c(C(N)=O)c2N)C1 |