Adrenomedullin (22-52) (human)
Adrenomedullin (22-52) (human) structure
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Common Name | Adrenomedullin (22-52) (human) | ||
|---|---|---|---|---|
| CAS Number | 159899-65-7 | Molecular Weight | 3576.03 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C159H252N46O48 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Adrenomedullin (22-52) (human)Adrenomedullin (AM) (22-52), human is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat. |
| Name | Adrenomedullin(22-52)(Human) |
|---|---|
| Synonym | More Synonyms |
| Description | Adrenomedullin (AM) (22-52), human is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat. |
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| Related Catalog | |
| Target |
Adrenomedullin receptor, CGRP receptor[1] |
| In Vitro | Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist[1]. |
| References |
| Molecular Formula | C159H252N46O48 |
|---|---|
| Molecular Weight | 3576.03 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Adrenomedullin receptor binding sites in rat brain and peripheral tissues.
Eur. J. Pharmacol. 474 , 165-174, (2003) The existence of specific adrenomedullin receptor binding sites was investigated using the agonist peptide fragment [125I]human adrenomedullin-(13-52) in rat brain, lung and vas deferens homogenates. ... |
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Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway.
J. Cell Physiol. 215 , 122-128, (2008) Adrenomedullin (ADM) has been shown to mediate multifunctional responses in cell culture and animal system such as regulation of growth and apoptosis. ADM stimulates the proliferation of osteoblasts i... |
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Adrenomedullin antagonist suppresses in vivo growth of human pancreatic cancer cells in SCID mice by suppressing angiogenesis.
Oncogene 22 , 1238-1242, (2003) Since it is reported that adrenomedullin (AM) upregulated by hypoxia inhibits hypoxic cell death, we examined the effects of AM antagonist (AM C-terminal fragment; AM(22-52)) on the growth of pancreat... |
| MFCD00282038 |
| Adrenomedullin (AM) (22-52), human |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Adrenomedullin (22-52) (human)
- Price: ￥Inquiry/1mg ￥Inquiry/1mg ￥6708.0/5mg ￥3338.0/1mg
- Purity: 97.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Adrenomedullin (22-52) (human) trifluoroacetate salt
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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