Cav 2.2 blocker 1

Modify Date: 2024-01-06 19:14:09

Cav 2.2 blocker 1 Structure
Cav 2.2 blocker 1 structure
Common Name Cav 2.2 blocker 1
CAS Number 1567335-29-8 Molecular Weight 424.96
Density N/A Boiling Point N/A
Molecular Formula C25H29ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cav 2.2 blocker 1


Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].

 Names

Name Cav 2.2 blocker 1

 Cav 2.2 blocker 1 Biological Activity

Description Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].
Related Catalog
Target

IC50: 1 nM (Cav 2.2)[1].

References

[1]. Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.

 Chemical & Physical Properties

Molecular Formula C25H29ClN2O2
Molecular Weight 424.96
Storage condition -20°C