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Cav 2.2 blocker 1

Names

[ CAS No. ]:
1567335-29-8

[ Name ]:
Cav 2.2 blocker 1

Biological Activity

[Description]:

Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Neurological Disease

[Target]

IC50: 1 nM (Cav 2.2)[1].


[References]

[1]. Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H29ClN2O2

[ Molecular Weight ]:
424.96

[ Storage condition ]:
-20°C

Related Compounds