BMY 45778

Modify Date: 2024-04-06 09:12:47

BMY 45778 structure	Common Name	BMY 45778
	CAS Number	152575-66-1	Molecular Weight	438.43
	Density	1.298g/cm3	Boiling Point	659.9ºC at 760 mmHg
	Molecular Formula	C₂₆H₁₈N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	352.9ºC

Use of BMY 45778

BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor[1].

Name	bmy 45778
Synonym	More Synonyms

Description	BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. Seiler SM, et al. [3-[4-(4,5-Diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (BMY 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cAMP levels, protein kinase, and iloprost binding. Prostaglandins. 1997 Jan;53(1):21-35.

Density	1.298g/cm3
Boiling Point	659.9ºC at 760 mmHg
Molecular Formula	C₂₆H₁₈N₂O₅
Molecular Weight	438.43
Flash Point	352.9ºC
Exact Mass	438.12200
PSA	98.59000
LogP	5.79400
Vapour Pressure	2.59E-18mmHg at 25°C
Index of Refraction	1.617

Tocris-1442

2-[3-[4-(4,5-diphenyl-1,3-oxazol-2-yl)-1,3-oxazol-5-yl]phenoxy]acetic acid

DC Chemicals Limited
China
Product Name: BMY 45778
Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/250mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: BMY 45778
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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