BI-2081

Modify Date: 2025-10-05 19:22:06

BI-2081 Structure
BI-2081 structure
 Common Name BI-2081
CAS Number 1458656-71-7 Molecular Weight 534.62
Density N/A Boiling Point N/A
Molecular Formula C32H35FO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-2081


BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].

 Names

Name BI-2081

 BI-2081 Biological Activity

Description BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].
Related Catalog
Target

GPR40 (FFAR1)[1]

References

[1]. Governa P, et al. FFAR1/GPR40: One target, different binding sites, many agonists, no drugs, but a continuous and unprofitable tug-of-war between ligand lipophilicity, activity, and toxicity. Bioorg Med Chem Lett. 2021 Jun 1;41:127969.

 Chemical & Physical Properties

Molecular Formula C32H35FO6
Molecular Weight 534.62
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Chemsrc provides BI-2081(CAS#:1458656-71-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of BI-2081 are included as well.>> amp version: BI-2081

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