Name | BI 186908 |
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Description | A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties. |
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References | References 1. Oost T, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3275-80. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR) |
Molecular Formula | C23H26N4O4 |
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Molecular Weight | 422.485 |