1453500-36-1
1453500-36-1 structure
- Name: BI 186908
- Chemical Name: BI 186908
- CAS Number: 1453500-36-1
- Molecular Formula: C23H26N4O4
- Molecular Weight: 422.485
- Create Date: 2020-01-20 10:57:55
- Modify Date: 2025-08-25 15:07:42
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A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties.
| Name | BI 186908 |
|---|
| Description | A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties. |
|---|---|
| References | References 1. Oost T, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3275-80. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR) |
| Molecular Formula | C23H26N4O4 |
|---|---|
| Molecular Weight | 422.485 |