2166387-64-8

2166387-64-8 structure

Name: BI-3812
Chemical Name: BI-3812
CAS Number: 2166387-64-8
Molecular Formula: C₂₆H₃₂ClN₇O₅
Molecular Weight: 558.03
Catalog: Research Areas Cancer
Create Date: 2018-09-02 12:37:20
Modify Date: 2024-01-05 17:41:36
BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.

Name	BI-3812

Description	BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	IC50: ≤3 nM (BCL6 BTB)[1]
In Vivo	BI-3812 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3812 shows an IC50 of 40 nM for the cellular BCL6[1].
References	[1]. Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.