BI-2081

Modify Date: 2024-04-11 12:33:45

BI-2081 structure	Common Name	BI-2081
	CAS Number	1458656-71-7	Molecular Weight	534.62
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₅FO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BI-2081

BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].

Name	BI-2081

Description	BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR40 Research Areas >> Metabolic Disease
Target	GPR40 (FFAR1)[1]
References	[1]. Governa P, et al. FFAR1/GPR40: One target, different binding sites, many agonists, no drugs, but a continuous and unprofitable tug-of-war between ligand lipophilicity, activity, and toxicity. Bioorg Med Chem Lett. 2021 Jun 1;41:127969.

Molecular Formula	C₃₂H₃₅FO₆
Molecular Weight	534.62

BI-2081

Use of BI-2081

Names

BI-2081 Biological Activity

Chemical & Physical Properties