Tiagabine hydrochloride hydrate

Modify Date: 2024-01-16 03:41:37

Tiagabine hydrochloride hydrate structure	Common Name	Tiagabine hydrochloride hydrate
	CAS Number	145821-57-4	Molecular Weight	430.02
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₈ClNO₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tiagabine hydrochloride hydrate

Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].

Name	Tiagabine hydrochloride hydrate

Description	Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Braestrup C, et al. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier. J Neurochem. 1990 Feb;54(2):639-47.

Molecular Formula	C₂₀H₂₈ClNO₃S₂
Molecular Weight	430.02
Storage condition	2-8℃

RIDADR	NONH for all modes of transport

Tiagabine hydrochloride hydrate

Use of Tiagabine hydrochloride hydrate

Names

Tiagabine hydrochloride hydrate Biological Activity

Chemical & Physical Properties

Safety Information