Benzenecarboximidamide hydrochloride hydrate

Modify Date: 2025-08-20 11:08:02

Benzenecarboximidamide hydrochloride hydrate structure	Common Name	Benzenecarboximidamide hydrochloride hydrate
	CAS Number	206752-36-5	Molecular Weight	174.628
	Density	N/A	Boiling Point	208.5ºC at 760mmHg
	Molecular Formula	C₇H₈N_2.ClH_.xH₂O	Melting Point	86-88 °C(lit.)
	MSDS	USA	Flash Point	79.9ºC

Use of Benzenecarboximidamide hydrochloride hydrate

Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1][2].

Name	benzenecarboximidamide,hydrate,hydrochloride
Synonym	More Synonyms

Description	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cancer
Target	Ki: 20 μM (Tryptase), 21 μM (Trypsin), 97 μM (uPA), 110 μM (Factor Xa), 320 μM (Thrombin), 750 μM (tPA)[1]
References	[1]. Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7(4):299-312. [2]. Tanizawa K, et al. Proteolytic enzymes. VI. Aromatic amidines as competitive inhibitors of trypsin. J Biochem. 1971 May;69(5):893-9.

Boiling Point	208.5ºC at 760mmHg
Melting Point	86-88 °C(lit.)
Molecular Formula	C₇H₈N_2.ClH_.xH₂O
Molecular Weight	174.628
Flash Point	79.9ºC
Exact Mass	174.055984
PSA	59.10000
LogP	2.50840
Vapour Pressure	0.213mmHg at 25°C
InChIKey	BQVJCMMLDJPBFZ-UHFFFAOYSA-N
SMILES	Cl.N=C(N)c1ccccc1.O
Storage condition	0-6°C
Water Solubility	soluble

MSDS(Chinese)

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CV6260000

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Benzenecarboximidamide hydrochloride hydrate

Benzamidine HCl Hydrate

MFCD00066285

Benzenecarboximidamide, hydrochloride, hydrate (1:1:1)

AMIDINOBENZENE HYDROCHLORIDE

Benzamidine hydrochloride, hydrate

Benzamidine hydrochloride hydrate

Benzamidine Hydrochloride Monohydrate

Benzamidinium chloride