NaPi2b-IN-1

Modify Date: 2025-08-26 18:46:06

NaPi2b-IN-1 Structure
NaPi2b-IN-1 structure
Common Name NaPi2b-IN-1
CAS Number 1453116-06-7 Molecular Weight 943.46
Density N/A Boiling Point N/A
Molecular Formula C44H58ClF3N4O11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NaPi2b-IN-1


NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia[1].

 Names

Name NaPi2b-IN-1

 NaPi2b-IN-1 Biological Activity

Description NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia[1].
Related Catalog
References

[1]. Maemoto M, et al. Discovery of Gut-Restricted Small-Molecule Inhibitors of Intestinal Sodium-Dependent Phosphate Transport Protein 2b (NaPi2b) for the Treatment of Hyperphosphatemia. J Med Chem. 2022;65(3):1946-1960.

 Chemical & Physical Properties

Molecular Formula C44H58ClF3N4O11S
Molecular Weight 943.46
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