2227445-31-8

2227445-31-8 structure
2227445-31-8 structure
  • Name: NaPi2b-IN-2
  • Chemical Name: NaPi2b-IN-2
  • CAS Number: 2227445-31-8
  • Molecular Formula: C41H47ClF3N5O5S
  • Molecular Weight: 814.36
  • Catalog: Research Areas Others
  • Create Date: 2022-07-13 21:12:22
  • Modify Date: 2025-08-26 23:29:06
  • NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia[1].

Name NaPi2b-IN-2
Description NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia[1].
Related Catalog
Target

IC50: 38 nM (human NaPi2b)[1]

References

[1]. Ushiki Y, et, al. Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4,5,6,7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors. Bioorg Med Chem Lett. 2022 Mar 1;59:128572.

Molecular Formula C41H47ClF3N5O5S
Molecular Weight 814.36
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